AOS

A PRIMER ON ENDOMETRIOSIS

Endometriosis is a complex and often misunderstood condition that affects millions of women worldwide. Despite its prevalence, many women remain unaware of the symptoms, available treatment options, and possible prevention strategies surrounding endometriosis.

What is Endometriosis?
Endometriosis is a chronic condition where tissue similar to the lining of the uterus, known as the endometrium, grows outside the uterus. These growths, called endometrial implants, can be found on the ovaries, fallopian tubes, bowel, and other pelvic organs. During the menstrual cycle, these implants may shed and bleed, leading to pain, inflammation, and the formation of scar tissue. These implants can also form cysts which, unlike common simple ovarian cysts, do not resolved by themselves and often require surgical therapy.

Recognizing Symptoms:
Endometriosis manifests differently in each woman, but common symptoms include:

1. Pelvic pain: Severe cramping, chronic pelvic pain, or lower back pain, typically experienced during menstruation.
2. Painful intercourse: Discomfort or pain during or after sexual intercourse.
3. Heavy or irregular periods: Menstrual bleeding that is abnormally heavy or irregular.
4. Gastrointestinal issues: Digestive problems such as bloating, constipation, or diarrhea, especially during menstruation.
5. Infertility: Difficulty conceiving or experiencing recurrent miscarriages.

Potential Causes:
While the exact cause of endometriosis remains unclear, several theories have been proposed. These include:

1. Retrograde menstruation: Menstrual blood flowing back through the fallopian tubes, depositing endometrial cells in the pelvis.
2. Genetic predisposition: Endometriosis may run in families, suggesting a genetic component.
3. Hormonal imbalance: Fluctuations in estrogen and progesterone levels may contribute to abnormal tissue growth.
4. Immune system dysfunction: An impaired immune response may allow endometrial cells to implant and grow in abnormal locations.

Diagnosis and Treatment:
Diagnosing endometriosis often involves a combination of medical history assessment, pelvic exams, imaging tests, and minimally invasive surgery called laparoscopy. Once diagnosed, several treatment options can be considered:

1. Pain management: Over-the-counter pain relievers or prescription medications may help alleviate symptoms.
2. Hormonal therapy: Birth control pills, hormonal patches, or progestin-based therapies can help regulate hormone levels and reduce symptoms. Newer medical therapies include GnRH blockers, such as
Orilissa and Myfembree.
3. Surgical intervention: Laparoscopic surgery can remove endometrial implants, scar tissue, and adhesions, providing relief and improving fertility prospects.
4. Lifestyle modifications: Engaging in regular exercise, managing stress, and adopting a healthy diet may help manage symptoms.

Conclusion:
Endometriosis is a complex and often misunderstood condition that can significantly impact a person's quality of life. By familiarizing ourselves with its symptoms, potential causes, and available treatment options, we can contribute to a more supportive and informed society. Let us strive to raise awareness, support those affected.